Abstract: In a separate report we demonstrated that B5 cluster antigens acts as a leading factor for ocular injuries. The question is why in some patients, these antigens does not produce the same lesions. This may be due to a genetic factor(s) which determine resistance to ocular lesions. Two HLA antigens attracted our attention as possible factors. One from the class I (CW4), and the other from the class II (DQW1). DQW1 ...
HLA-B5 cluster in non ocular type of Behcet's Disease (BD).
Abstract: We have reported a 100% association of ocular type of BD with B5 cluster antigens. The HLA results of non ocular type shows respectively 30% and 40% of association with B5 and B5 cluster antigens. These results indicate that B5 cluster antigens are decreased in non ocular patients compared to 62% of normal population. Considering the etiologic fraction for B5 cluster in ocular type patients which was at its maximum ...
HLA B5 cluster in the ocular form of Behcet's Disease (BD)
Abstract: The association of B5 and uveitis has been previously demonstrated. 37 patients with ocular form were studied for HLA, ABC and DR antigens, with a large panel of antisera (A.O.H.W.C panel sera). Results are: Antigen Control Patient Relative R. ...